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Docking Assessment demonstrated the existence of bioactive compounds inhibited TNFa, HER2, and MMP9 as being the target protein. The molecular dynamic final result was verified using molecular dynamic and it reveals that β-asarone conversation was steady in opposition to MMP9 and TNF protein confirmed from the very low RMSD benefit. The study uncovered the investigated bioactive compounds of Piper crocatum possess the activity of anti-cancer through the inhibition of TNFa and MMP9 protein. On the other hand, more analysis even now must be completed to verify the prediction effects of this In Silico research.
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